Drug Pathways Engine
Every Claim. Its Lowest Net Cost. Every Time.
A Drug Pathway is the optimal route to the lowest net cost on every drug, for every member, on every claim.
SmithRx: The #1 Modern PBM - YouTube
Three Dimensions. One Goal.
Every drug claim runs through all three dimensions simultaneously—not as a checklist, but as a single, continuous optimization.
The Right Drug
SmithRx evaluates every claim against clinically equivalent alternatives to find the lowest net cost option that works for the member.
The Right Place
The Right Price
How it Works: Meet the Drug Pathways Engine
A new generation of PBMs gave employers more visibility into drug spend. SmithRx built them an engine. One that identifies and routes every claim to the lowest net cost pathway, automatically.
Discovery
The Drug Pathways Engine continuously identifies the lowest net cost pathway available for every drug, across every dimension.
Routing
At the point of claim, the engine routes the member to the optimal pathway: the right drug, the right source, the right savings opportunities.
Execution
Drug pathways are carried out through multiple methods—such as automatic, clinical, and point-of-sale—with new approaches continuously being developed as the market evolves.
Drug Pathway Example: Weight Management
drugs
- Zepbound
- Wegovy
$11,700/year post rebates - Drug Selection
Low-list price GLP-1s
Prescribed by Weight Management Partner - Drug Source
Lilly/Direct
designated pharmacy
28-day supply - Cost Modifiers
Plan cost: $349 or less/month
Member copay: $100/month
savings: 50% savings per fill, $5,850/year
wrap around support: Clinical Care, $81/month fee per member
The Numbers Speak for Themselves
Every dollar of savings is real, reported, and traceable to a specific pathway decision.
- 20%+
Per Member Per Month Savings
Lower PMPM than the industry benchmark - $320M
Total 2025 Pathway Savings - $37
Average PMPM 2025 Pathways Savings
Built for Every Stakeholder
For Employers
Lower total pharmacy spend, access full data ownership, get measurable ROI.
For Brokers & Consultants
Fiduciary alignment you can trust—and a model that’s easy to explain.
For Members
Lower out-of-pocket costs and real human support that ensures continuity of care.
See Your Pharmacy Benefit Through the Drug Pathways Engine
Experience how real transparency and execution work together to reduce costs—without compromising care.
SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.